Author

Yuesang Lin

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Assay:spatial transcriptomics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:database / resource· 1

Frequent Co-Authors

Alyssa Rukshin· 1 shared Beth StevensiD· 1 shared Constanze DeppiD· 1 shared Dawei SuniD· 1 shared Eric Garcia· 1 shared Evan Z. MacoskoiD· 1 shared Fei CheniD· 1 shared Gord FishelliD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioinformatics

Alyssa Rukshin

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2 papers

Recent·Most cited

LARIS enables accurate and efficient ligand and receptor interaction analysis in spatial transcriptomics

Min Dai, Tivadar Torok, Dawei Sun, Vallari Shende, Grace Wang, Yuesang Lin, Sherry Jingjing Wu, Alyssa Rukshin, Gord Fishell, Fei Chen

LARIS identifies cell type-specific and spatially restricted ligand-receptor interactions in spatial transcriptomics data with high accuracy and scalability.

bioRxiv · Nov 26, 2025 · PreprintBioinformatics

Spatiotemporal Analysis of Remyelination Reveals a Concerted Interferon-Responsive Glial State That Coordinates Immune Infiltration

Michael-John Dolan, Raphael Rakosi-Schmidt, Eric Garcia, Yuesang Lin, Naeem M. Nadaf, Jessica Dixon, Shiran Guo, Nader Morshed, Constanze Depp, Jordan L. Doman, Judy Xia, Henna Jäntti, Beth Stevens, Evan Z. Macosko

This study uses spatial transcriptomics and single-nucleus RNA-seq to analyze remyelination dynamics, identifying an interferon-responsive glial state that coordinates immune infiltration and oligodendrocyte differentiation.

bioRxiv · Apr 22, 2025 · PreprintNeuroscience