Yungui He

Nanobody-Functionalized AAV achieves Promoter-independent Neuronal Targeting in the CNS

This paper develops AAV-m5, a nanobody-functionalized AAV vector that targets neurons via mGluR5, achieving efficient and specific transduction in the CNS without relying on promoters.

Protein Carrier AAV

This paper reports engineered AAV capsids that directly package proteins, demonstrating efficient delivery and activity of packaged proteins.

Efficient mesoscale phenotypic screening in cultured primary neuron culture

The paper develops an all-optical phenotypic screening system for cultured primary neurons to assess optogenetic actuators efficiently.