Author

Yupu Deng

Ottawa Hospital Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Duncan John StewartiD· 2 shared Anu Situ· 1 shared Brian Tran VaniD· 1 shared David P. CookiD· 1 shared Declan J. GaineriD· 1 shared Douglas QuiltyiD· 1 shared Emma R. McCourtiD· 1 shared Éric VivieriD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersDevelopmental Biology

Duncan John StewartORCID

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2 papers

Recent·Most cited

Natural killer cell TGF- signaling regulates senolytic activity and vascular patterning in the postnatal lung

Declan J. Gainer, Kassandra M. Coyle, Matthew T. Rätsep, Douglas Quilty, Brian Tran Van, Sofia I. Skebo, M. Martin VandenBroek, Kimberly J. Laverty, Yupu Deng, Jenna F. Alalouf, Shawyon P. Shirazi, Hugh J.M. Brady, Jennifer M. S. Sucre, Éric Vivier, Niraj Shrestha, , Mark L. Ormiston

This study shows that NK cell TGF-β signaling regulates postnatal lung development and BPD by affecting vascular patterning and senolytic activity.

Circulation Research · Oct 27, 2026Peer-reviewedDevelopmental Biology

Emergence of disease-specific endothelial and stromal cell populations responsible for arterial remodeling during development of pulmonary arterial hypertension

Nicholas D Cober, Emma R. McCourt, Rafael Soares Godoy, Yupu Deng, Kenny Schlosser, Anu Situ, David P. Cook, Sarah-Eve S Lemay, Timothy M. Klouda, Ke Yuan, Sébastien Bonnet, Duncan John Stewart

The paper uses scRNA-seq to identify disease-specific endothelial and stromal cell populations involved in arterial remodeling in PAH, highlighting TM4SF1 as a potential therapeutic target.

bioRxiv · Sep 6, 2023 · PreprintMolecular Biology