Author

C.-T. Tsai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biophysics· 2 Cell Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 5 Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Assay:imaging· 3 Research Focus:development & morphogenesis· 2 Organism:human· 2 Approach:microscopy & imaging analysis· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

B. Cui· 6 shared Z. Jahed· 5 shared X. Li· 4 shared W. Zhang· 3 shared Y. Yang· 3 shared A. R. Roy· 2 shared A. F. McGuire· 1 shared A. Illand· 1 shared

Activity by Year

2021-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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6 shared papersCell Biology

B. Cui

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Chromosome-level genome assemblies of two hemichordates provide new insights into deuterostome origin and chromosome evolution

C.-Y. Lin, F. Marletaz, A. Perez-Posada, P. M. Martinez Garcia, S. Schloissnig, P. Peluso, G. T. Conception, P. Bump, Y.-C. Chen, C. Chou, C.-Y. Lin, T.-P. Fan, C.-T. Tsai, J. L. Gomez Skarmeta, J. J. Tena, , Y.-H. Su

This study presents chromosome-level genome assemblies of two hemichordates to infer deuterostome ancestral chromosomal architecture and lineage-specific modifications.

bioRxiv · Nov 1, 2023Evolutionary Biology

Actin-Driven Nanotopography Promotes Stable Integrin Adhesion Formation in Developing Tissue

T. Chen, C. Huertas Fernandez-Espartero, A. Illand, C.-T. Tsai, Y. Yang, B. Klapholz, P. Jouchet, M. Fabre, O. Rossier, B. Cui, S. Leveque-Fort, N. H. Brown, G. Giannone

The paper shows that actin-driven membrane protrusions create nanotopographies that enable stable integrin adhesion in Drosophila muscle attachment sites.

bioRxiv · Jul 28, 2023Cell Biology

Engineering cell and nuclear morphology on nano topography by contact-free protein micropatterning

E. Sarikhani, D. Pushpa Meganathan, K. Rahmani, C.-T. Tsai, A. Marquez-Serrano, X. Li, F. Santoro, B. Cui, L. Hyldgaard Klausen, Z. Jahed

This study uses laser-assisted micropatterning to engineer cell and nuclear morphology on nanopillar platforms, showing disrupted nuclear-cell shape coupling and enhanced endocytosis on nanopillars.

bioRxiv · Jun 5, 2023 · PreprintBiophysics

Curved adhesions mediate cell attachment to soft matrix fibres in 3D

W. Zhang, C.-H. Lu, M. L. Nakamoto, C.-T. Tsai, A. R. Roy, C. E. Lee, Y. Yang, Z. Jahed, X. Li, B. Cui

This study identifies curved adhesions as a new type of integrin-mediated adhesion that forms in soft matrices and is crucial for 3D cell migration.

bioRxiv · Mar 16, 2023 · PreprintCell Biology

Nanocrown electrodes for reliable and robust intracellular recording of cardiomyocytes and cardiotoxicity screening

Z. Jahed, Y. Yang, C.-T. Tsai, E. P. Foster, A. F. McGuire, H. Yang, A. Liu, C. Forro, Z. Yan, X. Jiang, M.-T. Zhao, W. Zheng, X. Li, T. Li, A. Pawlosky, , B. Cui

This paper develops nanocrown electrodes for reliable intracellular recording of cardiomyocytes and demonstrates their use in cardiotoxicity screening.

bioRxiv · Sep 28, 2021 · PreprintBioengineering

Exploring cell surface-nanopillar interactions with 3D super-resolution microscopy

A. R. Roy, W. Zhang, Z. Jahed, C.-T. Tsai, B. Cui, W. E. Moerner

This paper introduces a 3D single-molecule super-resolution microscopy method to study protein distribution at the nano-bio interface with 10-20 nm precision.

bioRxiv · Jun 21, 2021Biophysics

Nanoscale surface topography reduces focal adhesions and cell stiffness by enhancing integrin endocytosis

X. Li, L. H. Klausen, W. Zhang, Z. Jahed, C.-T. Tsai, T. L. Li, B. Cui

This paper shows that nanoscale surface topography reduces focal adhesions and cell stiffness by enhancing integrin endocytosis, mimicking the effects of soft substrates on rigid materials.

bioRxiv · Jun 18, 2021Bioengineering