Topoisomerase I is an Evolutionarily Conserved Key Regulator for Satellite DNA Transcription
H. Liu, Z. Teng, L. Yang, Q. Zhang, Y. Chen, X. Wang, Y. Zheng, A. Tian, D. Tian, Z. Lin, W.-M. Deng
This study identifies Topoisomerase I as a conserved regulator of satellite DNA transcription across species, showing its role in centromere function and DNA damage response.
bioRxiv · May 3, 2024Cell Biology