Proteomic Profile of TGF-β1 treated Lung Fibroblasts identifies Novel Markers of Activated Fibroblasts in the Silica Exposed Rat Lung
N. Mao, H. Xu, F. Jin, D. Xu, D. Sales, H. Zhang, Z. Wei, S. Li, X. Gao, W. Cai, D. Li, G. Zhang, B. Zhang, L. Zhang, S. Li, , F. Yang
The paper identifies 196 differentially expressed proteins in TGF-β1-treated lung fibroblasts and finds that VLDLR and SDC2 are upregulated in silica-exposed lungs, with knockdown reducing collagen production.
bioRxiv · Oct 1, 2018Pharmacology & Toxicology