Author

Zakia Azmani

Erasmus MC

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Wilfred F. J. van IJckeniD· 2 shared Anne L. Kuijpers-Korporaal· 1 shared Cornelis Verhoef· 1 shared Danny HuylebroeckiD· 1 shared Debbie L.C. van den BergiD· 1 shared Dirk Jan GrünhageniD· 1 shared Hedda B. SomseniD· 1 shared Joachim BoersiD· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersDevelopmental Biology

Wilfred F. J. van IJckenORCID

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2 papers

Recent·Most cited

The Integrator complex prevents premature neuronal differentiation through global control of transcription elongation.

Hedda B. Somsen, Kristel N. Eigenhuis, Anne L. Kuijpers-Korporaal, Mariana Pelicano de Almeida, Roberto Montoro Ferrer, K. Peter Kats, Mike R. Dekker, Thuur Zuidweg, Zakia Azmani, Mirjam C. G. N. van den Hout, Wilfred F. J. van IJcken, Danny Huylebroeck, Maarten W.J. Fornerod, Raymond A. Poot, Debbie L.C. van den Berg

The paper shows that the Integrator complex regulates neuronal differentiation by controlling RNA polymerase II pause-release, and that disrupting this process leads to premature neuronal gene expression and developmental defects.

bioRxiv · Nov 26, 2024 · PreprintDevelopmental Biology

High throughput and affordable genome-wide methylation profiling of circulating cell-free DNA by Methylated DNA sequencing (MeD-seq) of LpnPI digested fragments

Teoman Deger, Ruben Boers, Vanja de Weerd, Lindsay Angus, Marjolijn M. J. van der Put, Joachim Boers, Zakia Azmani, Wilfred F. J. van IJcken, Dirk Jan Grünhagen, Lisanne F. van Dessel, Martijn P. Lolkema, Cornelis Verhoef, Stefan Sleijfer, John W.M. Martens, Joost H. Gribnau, Saskia M. Wilting

This paper validates MeD-seq for cfDNA methylation profiling in cancer patients, showing distinct pre-surgical methylation patterns compared to healthy donors.

Clinical Epigenetics · Oct 20, 2021Peer-reviewedGenomics