Author

Zhiying Wang

The University of Texas at Arlington

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Pharmacology & Toxicology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Marco A. P. BrottoiD· 2 shared Adina Israel· 1 shared Carl J. LovelyiD· 1 shared Charles V. MobbsiD· 1 shared Christopher P. CardozoiD· 1 shared Fred KoiD· 1 shared Jian Huang· 1 shared Jinzhu LiiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersPharmacology & Toxicology

Marco A. P. BrottoORCID

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Author profile →

3 papers

Recent·Most cited

Benzothiazole Derivatives as Dual Modulators of PGE2 and GABAergic Signaling in Skeletal Muscle

Marian N. Aziz, Kamal R. Awad, Jian Huang, Zhiying Wang, Venu Gopal Varanasi, Marco A. P. Brotto, Carl J. Lovely

This study identifies benzothiazole derivatives that modulate PGE2 and GABAergic signaling in skeletal muscle cells, with one compound downregulating Gabrg2, suggesting links between muscle signaling and neuropsychiatric disorders.

bioRxiv · Jun 3, 2026 · PreprintPharmacology & Toxicology

SUMO E1 covalent allosteric inhibitors modulate polyamine synthesis via the MAT2A-AdoMetDC axis

Shuai Zhang, Jinzhu Li, Zhiying Wang, Yutong Jiao, Xiaoyu Shi, Yuanbao Ai, Juanping Wang, Sen Liu

The paper identifies SUMO E1 covalent allosteric inhibitors that modulate polyamine synthesis through the MAT2A-AdoMetDC axis and show synergistic effects with polyamine inhibitors in T47D cells.

Bioorganic Chemistry · Aug 29, 2025Peer-reviewedPharmacology & Toxicology

RNA-sequencing reveals a gene expression signature in skeletal muscle of a mouse model of age-associated post-operative functional decline

Samantha Asche-Godin, Zachary A Graham, Adina Israel, Lauren M. Harlow, Weihua Huang, Zhiying Wang, Marco A. P. Brotto, Charles V. Mobbs, Christopher P. Cardozo, Fred Ko

This study uses RNA-sequencing to identify age-associated gene expression changes in skeletal muscle of mice after laparotomy, showing the greatest effects in younger mice.

The Journals of Gerontology Series A · Feb 16, 2022Peer-reviewedMolecular Biology