Author

Charles V. Mobbs

Icahn School of Medicine at Mount SinaiORCID 0000-0002-5815-8711Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2 Organism:C. elegans· 1 Research Focus:database / resource· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Aaron E. SilveriD· 1 shared Adina Israel· 1 shared Bik Tzu HuangiD· 1 shared Bin Zhang· 1 shared Boer Xie· 1 shared Chris GaiteriiD· 1 shared Christopher P. CardozoiD· 1 shared Christopher Paul KellneriD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperNeuroscience

Aaron E. SilverORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintSep 6, 2026

A Multi-Omics Study of Cognitive Resilience to Alzheimer's Disease

Erming Wang, Boer Xie, Minghui Wang…·Bin Zhang

The paper develops a multi-omics cohort of prefrontal cortex data from cognitively normal older adults to identify molecular signatures of cognitive resilience to Alzheimer's disease.

DOI 10.64898/2026.09.02.746746

humanproteomics

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NeurosciencebioRxivPreprintJun 12, 2023

Novel small molecules inhibit proteotoxicity and inflammation: Mechanistic and therapeutic implications for Alzheimer's Disease, healthspan and lifespan- Aging as a consequence of glycolysis

Rachel R Litke, James M. Vicari, Bik Tzu Huang…·Charles V. Mobbs

The paper identifies small molecules that inhibit proteotoxicity and inflammation in Alzheimer's Disease models, revealing mechanisms linking glycolysis to neuroinflammation and suggesting new therapeutic targets.

1 citation

C. elegansmouse

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Molecular BiologyThe Journals of Gerontology Series APeer-reviewedFeb 16, 2022

RNA-sequencing reveals a gene expression signature in skeletal muscle of a mouse model of age-associated post-operative functional decline

Samantha Asche-Godin, Zachary A Graham, Adina Israel…·Fred Ko

This study uses RNA-sequencing to identify age-associated gene expression changes in skeletal muscle of mice after laparotomy, showing the greatest effects in younger mice.

5 citations

mousebulk RNA-seq

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