Author

Yifan Zhang

Chinese Academy of Medical Sciences & Peking Union Medical CollegeORCID 0000-0002-0283-0468Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Yifan Zhang7 papers · University of California San Diego

Biology Disciplines

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Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Alexander JaworskiiD· 1 shared Alexandra Weiss· 1 shared Alper KüçükuraliD· 1 shared Diane LipscombeiD· 1 shared Emma M. ShychuckiD· 1 shared Haijing Shi· 1 shared Haruhiko BannoiD· 1 shared Heng Li· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperNeuroscience

Alexander JaworskiORCID

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2 papers

Recent·Most cited

Identification of a new ORF3a-E fusion subgenomic RNA of SARS-CoV-2 and its biological features in the infection process

Yifan Zhang, Huiwen Zheng, Jing Li, Xin Zhang, Jiali Li, Heng Li, Xin Zhao, Zihan Zhang, Yingyan Li, Keqi Chen, Shasha Peng, Ying Zhang, Haijing Shi, Longding Liu

The paper identifies a new SARS-CoV-2 subgenomic RNA, ORF3a-E-sgRNA, which enhances viral replication and immune evasion by promoting translation and host protein interactions.

Frontiers in Immunology · Aug 15, 2025Peer-reviewedMicrobiology

Up-regulation of cholesterol synthesis pathways and limited neurodegeneration in a knock-in Sod1 mutant mouse model of ALS.

Janice A. Dominov, Laura A. Madigan, Joshua P. Whitt, Katerina Rademacher, Kristin M. Webster, Hesheng Zhang, Haruhiko Banno, Siqi Tang, Yifan Zhang, Nicholas Wightman, Emma M. Shychuck, John Page, Alexandra Weiss, Karen L. Kelly, Alper Küçükural, , Robert H. Brown

This study shows that Sod1G85R knock-in mice exhibit up-regulated cholesterol synthesis pathways and limited neurodegeneration, contrasting with severe TgSOD1G93A mice, suggesting lipid pathway dysregulation in ALS.

bioRxiv · May 5, 2023 · PreprintNeuroscience