Author
Arkobrato Gupta
The Ohio State UniversityORCID 0000-0001-5026-3085Unclaimed ORCID profile · follow to get notified of new preprints
Biology Disciplines
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2024-2026 · peak 2/yrCo-Author Collaboration Network
10 top collaborators · 27 mutual co-author links5 papers
Recent·Most cited
- GeneticsMolecular PsychiatryPeer-reviewed
Genome-wide association study reveals multiple loci for nociception and opioid consumption behaviors associated with heroin vulnerability in outbred rats
Brittany N. Kuhn, Nazzareno Cannella, Apurva S. Chitre…·Abraham A. Palmer
This study identifies genetic loci associated with opioid use disorder-related behaviors in rats using a genome-wide association approach and network-based clustering.
17 citationstop 2% - NeuroscienceAmerican Journal of PsychiatryPeer-reviewed
A multi-symptomatic model of heroin use disorder in rats reveals distinct behavioral profiles and neuronal correlates of heroin vulnerability versus resiliency
Brittany N. Kuhn, Nazzareno Cannella, Ayteria D. Crow…·Peter W. Kalivas
This study uses a non-linear clustering approach in rats to identify distinct behavioral and neuronal profiles associated with heroin vulnerability and resiliency, reflecting human opioid use disorder heterogeneity.
11 citationstop 5% - ImmunologybioRxivPreprint
Identification of TAP2 protein variants resistant to inhibition by the HSV1 ICP47 protein
Gregory Nagy, Rebecca Presley, Shruti Dhar…·Jeffrey D. Parvin
The paper identifies TAP2 protein variants resistant to HSV1 ICP47 inhibition, which could lead to new antiviral therapies.
DOI 10.1101/2024.11.18.624061 - Cancer BiologybioRxivPreprint
Multiplexed functional analysis of TAP2 variants in regulating MHC-I cell surface abundance reveals overexpression of PLK1 downregulates antigen presentation.
Gregory Nagy, Rebecca Presley, Hyeongseon Jeon…·Jeffrey D. Parvin
The paper functionally screens TAP2 variants to show PLK1 overexpression reduces MHC-I surface abundance by phosphorylating TAP2, impairing antigen presentation in cancer cells.
2 citations