Jakub Faktor

Novel native serum peptidomics workflow enables the discovery of circulating subtype-specific peptide biomarkers in acute ischemic and haemorrhagic stroke

This paper introduces a novel serum peptidomics workflow that improves peptide yield, throughput, and recovery, identifying subtype-specific peptide biomarkers for stroke subtypes.

Benchmarking five extracellular vesicle proteomics workflows, including low-input Exo-insert and Exo-SP3, for deep mass spectrometry profiling

The paper benchmarks five proteomics workflows for sEV analysis, showing Exo-insert and Exo-SP3 can identify ~1100 proteins from low-input samples, with performance varying by sEV source.

Universal toolset for mass spectrometric analysis of intracellular peptidome and small protein fraction

The paper describes methods for isolating and analyzing short intracellular polypeptides and small proteins, along with computational tools for data analysis.

Multi-omics integration in Esophageal Adenocarcinoma reveals therapeutic targets and EAC-specific regulation of protein abundances

The paper identifies GPA33 as an EAC-specific biomarker and reveals post-transcriptional regulation of protein expression in EAC through multi-omics integration.