Author

Laurent Acquaviva

Memorial Sloan Kettering Cancer CenterORCID 0000-0001-5080-3619Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genetics· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 2 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1 Organism:yeast· 1

Frequent Co-Authors

Florencia PrattoiD· 2 shared Kevin BrickiD· 2 shared Mehmet E. KarasuiD· 2 shared Michiel BoekhoutiD· 2 shared R. Daniel Camerini‐OteroiD· 2 shared Scott KeeneyiD· 2 shared Agnès ThierryiD· 1 shared Amaury Bignaut· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMolecular Biology

Florencia PrattoORCID

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3 papers

Recent·Most cited

GeneticsbioRxivPreprintAug 28, 2023

Absence of chromosome axis proteins recruitment prevents meiotic recombination chromosome-wide in the budding yeast Lachancea kluyveri

Sylvain Legrand, Asma Saifudeen, Hélène Bordelet…·Bertrand Llorente

The paper shows that absence of Red1 and Hop1 recruitment prevents meiotic recombination on a chromosome arm containing the sex locus in Lachancea kluyveri, affecting genome evolution and fitness.

1 citation

yeastDNA methylation

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Molecular BiologyNaturePeer-reviewedMay 27, 2020

Ensuring meiotic DNA break formation in the mouse pseudoautosomal region

Laurent Acquaviva, Michiel Boekhout, Mehmet E. Karasu…·Scott Keeney

The paper identifies cis- and trans-acting factors that drive meiotic DNA break formation in the mouse pseudoautosomal region, revealing structural and molecular mechanisms essential for recombination and segregation.

111 citationstop 1%

mouseexperimental assay

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GeneticsMolecular CellPeer-reviewedApr 16, 2019

REC114 partner ANKRD31 controls number, timing and location of meiotic DNA breaks

Michiel Boekhout, Mehmet E. Karasu, Juncheng Wang…·Scott Keeney

This study identifies ANKRD31 as a regulator of meiotic DNA break formation in mice, showing its role in controlling DSB number, timing, and location, and linking its dysfunction to infertility.

114 citationstop 4%

mouseexperimental assay

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