Yu‐Peng Zhou

This study evaluates [18F]3F4AP PET imaging for detecting demyelination in traumatic brain injury models in mice, showing increased tracer uptake correlating with histological evidence of myelin loss.

This study introduces a PET tracer, [18F]3F4AP, to image demyelinated axons in spinal cord injuries and shows its ability to detect injury and monitor changes in animal models and humans.

This study shows that isoflurane anesthesia inhibits [18F]3F4AP metabolism in mice, leading to higher brain uptake, similar to human studies, and highlights the need to consider anesthesia effects in PET tracer translation.

This study evaluates two fluorinated gabapentin derivatives for brain PET imaging of 2{delta} receptors in rhesus macaques, showing differential brain uptake and displacement characteristics.

The paper describes the synthesis and evaluation of [11C]3Me4AP, a tracer for imaging Kv1 channels in the CNS, showing lower brain uptake and slower kinetics compared to related tracers.

This paper develops two 18F-labeled gabapentin derivatives for imaging the α2δ-1 subunit of calcium channels in neuropathic pain, showing increased uptake in injured nerves.

This paper develops and evaluates [11C]3MeO4AP, a PET tracer for imaging potassium channels in the CNS, showing high brain permeability, metabolic stability, and sensitivity to brain injury.