Amaury François

This paper introduces a method to control endogenous nicotinic receptors in mice using light-activated drug release, revealing circuit-specific effects previously hidden by systemic administration.

The paper identifies a specific neural circuit between the ACC and dlPAG that facilitates the affective component of pain, showing its role in aversive behaviors beyond pain.

This study investigates mechanical itch hypersensitivity in Shank3 mutant mice, finding somatosensory deficits and two pathways regulating itchiness.

The paper demonstrates that Cav3.2 calcium channels are expressed in human DRG neurons and exhibit sex dimorphism, supporting their role in pain mechanisms.

This study investigates the role of T-type calcium channel Cav3.2 in PKCγ neurons of the spinal dorsal horn during chronic pain, showing its involvement in synaptic and intrinsic activity changes but not in firing properties.

This study shows that C-LTMRs in mice influence social behavior and affective touch, with their dysfunction leading to social isolation and increased excitability promoting pro-social interactions.

This paper develops light-inducible methods to activate TrkA signaling without NGF, enabling precise spatial and temporal control of neuronal signaling pathways.