Marina Herwerth

This paper introduces an in vivo model for focal astrocyte ablation combined with longitudinal two-photon imaging to study CNS responses to astrocyte loss.

This study shows that in a mouse model of NMOSD, demyelination occurs due to off-target complement injury to oligodendrocytes, not directly from astrocyte loss.

This study identifies meningeal monocyte-derived macrophages as drivers of progressive multiple sclerosis using single-cell and spatial transcriptomics.

The paper shows that mature astrocytes can transform into progenitor-like cells to regenerate astrocytic networks after injury in mice.