Author

Sarah Mundt

University of ZurichORCID 0000-0003-2169-2109Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 4 Research Focus:cell type annotation· 3 Approach:deep learning· 2 Approach:experimental assay· 2 Assay:flow cytometry· 2 Research Focus:host-pathogen & immune response· 2 Assay:scRNA-seq· 2 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

Burkhard BecheriD· 4 shared Juan Villar-VesgaiD· 3 shared Deborah GreisiD· 2 shared Donatella De FeoiD· 2 shared Elèni Meuffels· 2 shared Florian IngelfingeriD· 2 shared Francesco PriscoiD· 2 shared Jeanne KimiD· 2 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersImmunology

Burkhard BecherORCID

Mutual co-authors in cluster

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4 papers

Recent·Most cited

ImmunologybioRxivPreprintJan 11, 2026

IL-12R signaling promotes type 1 regulatory T cell specialization by sustaining T-bet

Anna Estrada Brull, Ylva M. Carlen, Laura Revert Rubio…·Nicole Joller

This study shows IL-12R signaling sustains T-bet in Treg cells, promoting type 1 specialization and enhancing suppressive function against Th1 responses.

DOI 10.64898/2026.01.10.698646

mousehuman

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ImmunologybioRxivPreprintAug 15, 2025

Mapping Leukocyte Dynamics during Neuroinflammation Identifies Meningeal Monocyte-Derived Macrophages as Drivers of Progressive Disease

Juan Villar-Vesga, Pauline Clément, Hannah Van Hove…·Sarah Mundt

This study identifies meningeal monocyte-derived macrophages as drivers of progressive multiple sclerosis using single-cell and spatial transcriptomics.

DOI 10.1101/2025.08.15.670462

mousescRNA-seq

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ImmunologyCell ReportsPeer-reviewedMay 1, 2025

Regulatory T cells control type 1-driven immunopathology restraining GM-CSF-producing helper T cells

Sara Costa-Pereira, Margit Lanzinger, Myrto Andreadou…·Burkhard Becher

This study identifies GM-CSF-producing helper T cells as drivers of immunopathology, showing Treg cells restrain them to prevent tissue damage in mice.

3 citations

mouseflow cytometry

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ImmunologybioRxivPreprintSep 18, 2024

Monocyte-derived cells but not Microglia cause Oxidative Tissue Damage in Neuroinflammation

Juan Villar-Vesga, Donatella De Feo, Pauline Clément…·Sarah Mundt

The paper identifies monocyte-derived cells as the primary source of ROS-mediated oxidative tissue damage in neuroinflammation, distinct from microglia.

2 citations

mousescRNA-seq

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