Keri‐Lyn Kozul

This study identifies sequence elements that enable dual localization of mitochondrial proteins, showing how combinatorial features regulate import and function across compartments.

The paper identifies ARMC1 as a repressor of mitophagy that interacts with TMEM11, BNIP3, and NIX, and shows TMEM11 antagonizes PPTC7 to protect receptors during mitophagy activation.

This study identifies PPTC7 as a cofactor for SCFFBXL4-mediated degradation of BNIP3 and NIX, suppressing mitophagy and revealing a feedback mechanism to regulate mitochondrial homeostasis.

This paper shows that PPTC7 limits mitophagy by interacting with BNIP3 and NIX, promoting their proteasomal degradation through dynamic, proximal associations.