Dick Schijven

The paper uses connectopic mapping on UK Biobank data to analyze variation in language-related brain connectivity and identifies genetic loci associated with these patterns.

This study integrates brain structure and function to identify genetic loci associated with language-related brain components using UK Biobank data.

The paper investigates the phenotypic effects of archaic protein-altering variants in living humans using UK Biobank data, finding no significant differences in health or cognitive traits among carriers.

This study functionally characterizes SATB2 missense variants to identify distinct effects on chromatin binding and transcriptional activity, revealing partial loss-of-function and some variants with increased function.

The paper identifies distinct brain structural impacts of polygenic dyslexia disposition in adults using large-scale population data.

The paper uses imaging genetics to analyze functional connectivity in language networks, identifying genetic loci linked to language abilities, dyslexia, and handedness.

This study identifies rare protein-altering variants in TUBB4B and other genes associated with left-handedness using exome data from over 300,000 individuals.

The paper identifies 28 genomic loci associated with endocranial globularity using imaging genomics data from over 33,000 adults and links them to brain development and other physiological systems.

The paper identifies 355 genomic loci associated with white matter connectivity in the human brain, linking them to neurodevelopmental processes and polygenic risk for brain disorders.

The paper shows inherited CHD3 variants cause Snijders Blok-Campeau syndrome with variable expressivity, overlapping with de novo variants' phenotypes, and suggests reduced penetrance is not due to expression compensation.

The paper associates left-handedness with structural brain asymmetries in specific cortical regions using data from 31,864 individuals and identifies genetic links to these asymmetries.

The paper identifies 21 genetic loci associated with brain asymmetry using UK Biobank data and links them to microtubule-related genes and psychiatric traits.

The paper analyzes brain asymmetry in three population datasets, finding associations with handedness, cognitive functions, and a genetic correlation with Autism Spectrum Disorder.

This study identifies strong genetic correlations between genetic generalized epilepsy and background EEG oscillations, particularly in the beta frequency band, suggesting shared biological mechanisms.

The paper identifies nine clinical phenotypes and polygenic risk scores associated with quality of life in schizophrenia patients and their relatives.

This study uses pathway analysis on schizophrenia GWAS data to identify enrichment in synaptic plasticity and neurotransmitter synapse gene sets, supporting a role for postsynaptic signaling in schizophrenia.