Bochao Danae Lin

This study identifies cell-type-specific DNA methylation dynamics in the human cortex across development, highlighting prenatal periods as critical for epigenomic plasticity and linking changes to neurodevelopmental disorders.

The paper replicates an antidepressant response polygenic risk score (PRS-AR) in an independent trial and shows drug-specific effects and improved remission rates with stratification.

The paper integrates single-cell transcriptomic data with genome-wide association studies to identify neuronal cell types consistently implicated in neuropsychiatric disorders.

This study identifies strong genetic correlations between genetic generalized epilepsy and background EEG oscillations, particularly in the beta frequency band, suggesting shared biological mechanisms.

The paper identifies nine clinical phenotypes and polygenic risk scores associated with quality of life in schizophrenia patients and their relatives.

The paper identifies genetic differences in BMI between tall and short individuals using UK Biobank data, finding height-specific loci and differential effects on BMI and related traits.

The paper investigates how polygenic risk for schizophrenia interacts with childhood adversity to influence emotional dysregulation and psychosis proneness in adolescents and young adults.

This study uses Mendelian randomization to examine if genetic variants influencing C-reactive protein levels are associated with post-ICU PTSD and depression, finding no significant associations.