Clyde Francks

The paper uses connectopic mapping on UK Biobank data to analyze variation in language-related brain connectivity and identifies genetic loci associated with these patterns.

This study examines brain asymmetry in situs inversus totalis cases, finding no significant difference in functional asymmetries between genetically solved and unsolved cases, but altered structural asymmetries regardless of genetic cause.

This study integrates brain structure and function to identify genetic loci associated with language-related brain components using UK Biobank data.

The paper investigates the phenotypic effects of archaic protein-altering variants in living humans using UK Biobank data, finding no significant differences in health or cognitive traits among carriers.

This study functionally characterizes SATB2 missense variants to identify distinct effects on chromatin binding and transcriptional activity, revealing partial loss-of-function and some variants with increased function.

The paper uses spatial transcriptomics to analyze left-right gene expression and cell type differences in mouse brain regions, finding transcriptional asymmetries but no significant cell type abundance differences.

This study presents the first spatial transcriptomic data from a chimpanzee brain, mapping gene expression and cell types in the frontal pole and integrating with single-nucleus transcriptomics to explore evolutionary differences.

The paper identifies distinct brain structural impacts of polygenic dyslexia disposition in adults using large-scale population data.

The paper conducts GWAS on brain volumes, identifies genetic loci, and develops polygenic scores with cross-ancestry predictive ability and causal links to neuropsychiatric disorders.

The paper uses imaging genetics to analyze functional connectivity in language networks, identifying genetic loci linked to language abilities, dyslexia, and handedness.

This study uses machine learning to analyze brain asymmetry across aging and diseases, revealing left-hemisphere changes that challenge the traditional right-hemisphere aging model.

The paper identifies region-specific laminar gene expression patterns in language-related cortical areas and links them to structural connectivity and dyslexia risk.

This study identifies hemispheric asymmetry in mouse brains, revealing species-specific patterns and differences from humans, with implications for autism research.

This study identifies rare protein-altering variants in TUBB4B and other genes associated with left-handedness using exome data from over 300,000 individuals.

The paper identifies 28 genomic loci associated with endocranial globularity using imaging genomics data from over 33,000 adults and links them to brain development and other physiological systems.

The paper analyzes cortical asymmetry across age and datasets, finding stable areal asymmetry and developmental changes in thickness asymmetry, with genetic and phenotypic associations.

The paper identifies 355 genomic loci associated with white matter connectivity in the human brain, linking them to neurodevelopmental processes and polygenic risk for brain disorders.

The paper shows inherited CHD3 variants cause Snijders Blok-Campeau syndrome with variable expressivity, overlapping with de novo variants' phenotypes, and suggests reduced penetrance is not due to expression compensation.

The paper examines hemispheric asymmetry in structural covariance networks in ASD across 43 datasets, finding altered topological features in specific brain regions.

This study identifies divergent patterns of atypical cortical asymmetry and regional atrophy in temporal lobe epilepsy using MRI data from a large multi-site cohort.

The paper associates left-handedness with structural brain asymmetries in specific cortical regions using data from 31,864 individuals and identifies genetic links to these asymmetries.

The paper identifies 21 genetic loci associated with brain asymmetry using UK Biobank data and links them to microtubule-related genes and psychiatric traits.

The paper analyzes brain asymmetry in three population datasets, finding associations with handedness, cognitive functions, and a genetic correlation with Autism Spectrum Disorder.

The paper examines the relationship between hemispheric grey matter asymmetry and auditory processing of spoken syllables in 281 adults, finding structural correlates in subcortical regions.

The paper assesses reproducibility in brain MRI research by re-analyzing hemispheric effects across multiple datasets, finding an average reproducibility rate of 63.2%.

The paper investigates the genetic basis of situs inversus totalis (SIT) in 15 individuals, finding no clear monogenic links and suggesting complex genetic or environmental factors.

The paper identifies genes correlated with the sentence-processing network in the human cortex using gene expression, fMRI, and neuroimaging meta-analysis.

The paper investigates genetic factors influencing planum temporale asymmetry and finds limited genetic links to neurodevelopmental disorders, intelligence, or educational attainment.

This study identifies altered structural brain asymmetry in autism spectrum disorder using a large-scale meta-analysis of MRI data from 1,774 ASD cases and 1,809 controls.