Author

Ahmed A. A. Amine

University of California, San FranciscoORCID 0000-0001-5211-784XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Approach:experimental assay· 2 Organism:yeast· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Approach:statistical model· 1

Frequent Co-Authors

Bassem Al‐SadyiD· 2 shared Agnisrota MazumderiD· 1 shared Can GoksaliD· 1 shared Catherine TaniD· 1 shared Dana R Kennedy· 1 shared Eric SimentaliD· 1 shared Eric W. MartiniD· 1 shared Ilya J. FinkelsteiniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMolecular Biology

Bassem Al‐SadyORCID

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2 papers

Recent·Most cited

Phosphorylation of HP1/Swi6 relieves competition with Suv39/Clr4 on nucleosomes and enables H3K9 trimethyl spreading.

Dana R Kennedy, Joël P.C. Lemiere, Ahmed A. A. Amine, Eric W. Martin, Catherine Tan, Eric Simental, Julian R. Braxton, Robert A. Maxwell, Bassem Al‐Sady

This study shows that phosphorylation of HP1/Swi6 reduces competition with Suv39/Clr4 by altering its nucleosome affinity and oligomerization, promoting H3K9me3 spreading in S. pombe.

Nucleic Acids Research · Oct 22, 2025Peer-reviewedMolecular Biology

Discrete Subdomains Establish Epigenetic Diversity in Subtelomeric Heterochromatin

Agnisrota Mazumder, John P Cooper, Can Goksal, Rosario Y. J. Brockhausen, Jonas M. Schauß, Jasbeer Singh Khanduja, Richard Inho Joh, Ahmed A. A. Amine, Johannes J Groos, Junko Kanoh, Mo Motamedi, Ilya J. Finkelstein, Bassem Al‐Sady, Sigurd J Braun

The paper identifies distinct epigenetic subdomains in subtelomeric heterochromatin of S. pombe, showing position-specific silencing and the role of structural variants in epigenetic stability.

bioRxiv · Sep 25, 2025 · PreprintGenomics