Author

Lauren C. Guttman

Johns Hopkins UniversityORCID 0000-0001-5221-4236Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1

Frequent Co-Authors

Aanishaa JhaldiyaliD· 1 shared Abhay Monghekar· 1 shared Abhishek Pasupuleti· 1 shared Akansha Aggarwal· 1 shared Akira SawaiD· 1 shared Amy Yuan· 1 shared Anning Cui· 1 shared Chloe D. Holland· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperNeuroscience

Aanishaa JhaldiyalORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

NeurosciencebioRxivPreprintSep 18, 2025

Screening of a kinase inhibitor library in human Huntington disease iPSC derived striatal precursor neurons reveals a neuroprotective effect of PKC alpha and PKC beta1 inhibition

Mali Jiang, Tianze Shi, Ritika Miryala…·Christopher A. Ross

The paper screens a kinase inhibitor library in HD iPSC-derived neurons to identify PKC alpha and beta1 inhibition as neuroprotective against mutant huntingtin toxicity.

DOI 10.1101/2025.09.18.677178

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintSep 6, 2025

Poly(ADP-ribose) Polymerase 1 Deficiency Attenuates Amyloid Pathology, Neurodegeneration, and Cognitive Decline in a Familial Alzheimer Disease Model

Aanishaa Jhaldiyal, Manisha Kumari, Trupti Tripathi…·Valina Lynn Dawson

This study shows PARP1 inhibition reduces amyloid pathology, neurodegeneration, and cognitive decline in a mouse model of Alzheimer's disease.

3 citations

mouseproteomics

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 19, 2021

The anterior insular cortex associates temporally discontiguous stimuli during threat learning

Ho Namkung, Sedona Lockhart, Josephine de Chabot…·Akira Sawa

This study identifies the role of the anterior insular cortex in associating temporally discontiguous stimuli during threat learning in mice.

1 citation

mouseelectronic health records

𝕏 PostBluesky