Minja Velimirovic

This paper uses prime editing to classify LDLR variants by measuring their impact on LDL-C uptake, reclassifying many previously unclassified variants.

This study identifies 21 genes whose rare variants affect LDL-C levels by altering cholesterol uptake, using CRISPR screening and co-essentiality analysis.

This study identifies genetic pathways involved in remdesivir cytotoxicity using CRISPR-Cas9 screening and transcriptomics, finding that SLC29A3 and AK2 are key factors in toxicity and efficacy.

This paper engineers CRISPR-Cas9 variants from Streptococcus thermophilus to target diverse A-rich PAMs, enabling efficient genome editing in mice.