Kristina A. Matkowskyj

This study identifies versikine, a matrikine derived from VCAN proteolysis, as essential for organizing dendritic cell-T cell triads in tertiary lymphoid structures and enhancing antitumor immunity.

This study develops a mouse model of DNAJB1-PRKACA fusion and shows it drives biliary and pancreatic carcinogenesis, with pre-invasive features and Slc16a14 as a biomarker for malignant transformation.

STpath translates histopathology image embeddings into cell-type composition and gene expression estimates for clinical applications.

This study shows that invasive cancer can develop and regress within weeks after papillomavirus infection in mice, highlighting the rapid progression and immune dependence of tumor regression.