Cell BiologyCell Death and DiseasePeer-reviewed
Mechanism by which Aurora B inhibitors promotes RB and p53-dependent senescence.
Shivam Vora, Saptarshi Chatterjee, Ariel Andrew…·Brian G. Gabrielli
This study investigates how Aurora B inhibitors induce polyploidy and shows that higher ploidy states reduce long-term proliferative potential in cells with functional RB and p53.
11 citations