Author

Deborah Nazareth

Children's Medical Research InstituteORCID 0000-0002-5983-3571Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Leszek LisowskiiD· 2 shared Maddison KnightiD· 2 shared Marti Cabanes‐CreusiD· 2 shared Ramon Roca-PinillaiD· 2 shared Sophia H.Y. Liao· 2 shared Adrian WesthausiD· 1 shared Adriana Lucely RojasiD· 1 shared Aitor HierroiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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2 shared papersCell Biology

Leszek LisowskiORCID

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Author profile →

3 papers

Recent·Most cited

AAV2 Bypasses Direct Endosomal Escape by Using AAVR to Access the Trans-Golgi Network en Route to the Nucleus.

Marti Cabanes‐Creus, Sophia H.Y. Liao, Marta Pardo-Piñón, Adriana Lucely Rojas, Joseph M. Kelich, Jackson Coyne, Maddison Knight, Deborah Nazareth, Ramon Roca-Pinilla, Sujata Senapati, Matthew C. Walsh, Pedro Joel Cejas, Sean M. Armour, Aitor Hierro, Leszek Lisowski

This study shows AAV2 bypasses endosomal escape by using AAVR to access the trans-Golgi network, challenging the model of direct endosomal escape.

Journal of Virology · Jul 29, 2026Peer-reviewedCell Biology

Mechanism by which Aurora B inhibitors promotes RB and p53-dependent senescence.

Shivam Vora, Saptarshi Chatterjee, Ariel Andrew, Ramyashree Prasanna Kumar, Martina A. Proctor, Zhen Zeng, Rituparna Bhatt, Deborah Nazareth, Madushan Fernando, Mathew V. Jones, Yaowu He, John David Hooper, Nigel A.J. McMillan, Jelena Urosevic, Jamal Carlos Saeh, , Brian G. Gabrielli

This study investigates how Aurora B inhibitors induce polyploidy and shows that higher ploidy states reduce long-term proliferative potential in cells with functional RB and p53.

Cell Death and Disease · Jan 8, 2025Peer-reviewedCell Biology

Harnessing the power of whole human liver ex situ normothermic perfusion for preclinical AAV vector evaluation

Marti Cabanes‐Creus, Sophia H.Y. Liao, Renina Gale Navarro, Maddison Knight, Deborah Nazareth, Ngee‐Soon Lau, Mark Ly, Erhua Zhu, Ramon Roca-Pinilla, Ricardo Bugallo, Ana F. Vicente, Grober Baltazar, Adrian Westhaus, Jessica Merjane, Michael W. Crawford, , Leszek Lisowski

This study evaluates AAV vectors in human liver explants under normothermic perfusion to assess their functionality and neutralization by human sera.

Nature Communications · Mar 14, 2024Peer-reviewedMolecular Biology