Jing Chen

This study shows that anaphase synchrony in fission yeast depends on rapid securin degradation and is limited by molecular noise, without requiring positive feedback.

This study investigates how Aurora B inhibitors induce polyploidy and shows that higher ploidy states reduce long-term proliferative potential in cells with functional RB and p53.

This paper uses mathematical modeling to show that rhythmic deadenylation is the main driver of poly(A) tail length rhythms and mRNA translatability in circadian gene expression.