Evren Alici

The paper decodes correlated dynamics at the pMHC interface to understand TCR recognition and immunogenicity using computational methods.

This study develops DARPin T cell engagers that specifically target HLA/peptide complexes on tumor cells, showing high affinity and specificity through in vitro selection and structural analysis.

This paper develops hPep-based nanoparticles for efficient delivery of gene editors across multiple cell types, achieving high editing efficiency in human cells.

This study characterizes the conformational dynamics of G3BP1 under different pH conditions and shows how its structural changes enable phase separation.

The paper determines the crystal structure of PsrSp and uses NMR to analyze its dynamics, showing that four long loops contribute to ligand specificity through their mobility.