Lydia L. Good

This study examines how protein language models handle intrinsically disordered proteins, finding they encode structural and functional information despite reduced attention on disordered regions.

This study uses acoustic trapping to measure the mechanical properties of single biopolymer condensates, showing it can detect changes in bulk modulus under different environmental conditions.

The paper develops RFdiffusion to generate protein binders for IDPs/IDRs, achieving nanomolar affinity and functional applications in amylin and IL2RG.