Author

Xiaoqing Cheng

Washington University in St. LouisORCID 0000-0001-5321-1459Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cancer Biology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell type annotation· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Ian S. HagemanniD· 2 shared Jacob HsiaiD· 2 shared Julie L. PrioriD· 2 shared Maureen K. HighkiniD· 2 shared Ron BoseiD· 2 shared Albert Kim· 1 shared Amanda E.D. Van SwearingeniD· 1 shared Ann BialikiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

Ian S. HagemannORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 28, 2026

Combined Loss of VHL and TSC1 Drives Clear Cell Renal Cell Carcinoma with Metabolic and Redox Reprogramming that Creates an NRF2 Dependency

Jianing Xu, Xiaoqing Cheng, Omran Abu Aboud…·James J.-D. Hsieh

This study creates a mouse model of VHL-/-TSC1-/- ccRCC, identifies metabolic and redox reprogramming, and highlights NRF2 as a therapeutic target.

DOI 10.64898/2026.09.24.754188

mousebulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJul 6, 2025

HER2; p53 Co-mutated Cancers Show Increased Histone Acetylation and are Sensitive to Neratinib plus Trastuzumab Deruxtecan.

Xiaoqing Cheng, Jacob Hsia, Jesus Iraheta…·Ron Bose

This study shows that HER2 and TP53 co-mutant cancers have increased histone acetylation and are sensitive to neratinib plus trastuzumab deruxtecan.

DOI 10.1101/2025.07.06.663368

mouseexperimental assay

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJun 17, 2025

Cerebellum metastasis model of HER2-positive breast cancer unveils key role of IL34-induced Arg1+ macrophages.

Xiaoqing Cheng, Khooshbu Kantibhai Patel, Brandon Zhou…·Ron Bose

This paper develops a mouse model of HER2-positive breast cancer cerebellar metastases and identifies IL34-induced Arg1+ macrophages as key drivers of tumor growth, showing that targeting CSF1R can reduce metastases.

1 citation

mousespatial transcriptomics

𝕏 PostBluesky