NeurosciencebioRxivPreprint
PGC-1α and PPARs cooperatively mediate photoreceptor neuroprotection in rd1 mouse inherited retinal degeneration
Lan Wang, Jie Yan, Javier Sancho-Pellúz…·François Paquet‐Durand
This study investigates the role of PPARs and PGC-1α in photoreceptor neuroprotection in rd1 mouse model of retinal degeneration, finding that their activation reduces photoreceptor death and PARP activity.
DOI 10.1101/2025.10.21.683632