Nicolas Brouilly

The Joubert syndrome protein CSPP1 is a conserved regulator of vertebrate multiciliogenesis and motile cilia function

This study identifies CSPP1 as a conserved regulator of multiciliogenesis and motile cilia function in vertebrates, showing its role in centriole amplification, basal body migration, and ciliary structure and function.

Deciphering the dynamic proteome of multiciliated cells

This study generates a stable MCC line to profile proteome dynamics during differentiation, identifying CDK7 as a critical regulator in Xenopus and human systems.

A novel membrane contact site in vestibular hair cells

The paper describes a novel membrane contact site in mouse type I vestibular hair cells associated with atypical plasma membrane-apposed mitochondria, potentially modulating non-quantal transmission.

C. elegans epicuticlins define specific compartments in the apical extracellular matrix and function in wound repair

This study identifies the localization and function of C. elegans epicuticlins in the apical extracellular matrix, showing their role in wound repair.

Titin-dependent biomechanical feedback tailors sarcomeres to specialised muscle functions in insects

The paper identifies a titin-dependent biomechanical feedback mechanism that adjusts sarcomere structure to meet the functional demands of different insect muscle types.

Myofibril and mitochondria morphogenesis are coordinated by a mechanical feedback mechanism in muscle

The paper shows that myofibril and mitochondria morphogenesis in Drosophila muscles are coordinated by a biomechanical feedback mechanism involving spalt and mitochondrial dynamics.