ImmunologybioRxivPreprint
Bcl-2 protein Noxa is required for metabolic reprogramming to glutamine dependence and for apoptosis in stimulated human CD8+ T cells
Tingyuan Yang, Himani Sharma, Jenna M. Benson…·Ameeta Kelekar
This study identifies Noxa's role in metabolic reprogramming to glutamine dependence in CD8+ T cells, independent of its canonical apoptotic function, and suggests its potential as an immunotherapeutic target.
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