Author

Christopher A. Pennell

University of MinnesotaORCID 0000-0002-2901-6554Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1

Frequent Co-Authors

Ameeta KelekariD· 1 shared Beau R. WebberiD· 1 shared Branden S. MoriarityiD· 1 shared Himani Sharma· 1 shared Jenna M. Benson· 1 shared Rebecca S. LaRueiD· 1 shared Stephen C. JamesoniD· 1 shared Tingyuan YangiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperImmunology

Ameeta KelekarORCID

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1 paper

Recent·Most cited

Bcl-2 protein Noxa is required for metabolic reprogramming to glutamine dependence and for apoptosis in stimulated human CD8+ T cells

Tingyuan Yang, Himani Sharma, Jenna M. Benson, William J. Valente, Rebecca S. LaRue, Beau R. Webber, Branden S. Moriarity, Christopher A. Pennell, Stephen C. Jameson, Ameeta Kelekar

This study identifies Noxa's role in metabolic reprogramming to glutamine dependence in CD8+ T cells, independent of its canonical apoptotic function, and suggests its potential as an immunotherapeutic target.

bioRxiv · Dec 10, 2025 · PreprintImmunology