SARS-CoV-2 Omicron Envelope T9I adaptation confers resistance to autophagy
Susanne Klute, Rayhane Nchioua, Arne Cordsmeier, Jyoti Vishwakarma, Lennart Koepke, Hala Alshammary, Christoph Jung, Maximilian Hirschenberger, Helene Hoenigsperger, Jana-Romana Fischer, Rinu Sivarajan, Fabian Zech, Steffen Stenger, Ruth Serra-Moreno, Ana Silvia Gonzalez-Reiche, , Konstantin M. J. Sparrer
The paper shows that the T9I mutation in the SARS-CoV-2 E protein confers autophagy resistance in Omicron variants, contributing to their spread.
iScience · Jun 20, 2025Peer-reviewedMicrobiology