Isaac Henry Bianco

Predatory orienting is jointly controlled by optic tectum and pretectum.

This study identifies how the optic tectum and pretectum coordinate to control predatory orienting in larval zebrafish through distinct neural pathways.

Neural microexons modulate arousal states via cAMP signalling in zebrafish

This study shows that srrm3 regulates arousal states in zebrafish via cAMP signaling, with mutations causing hyperarousal and transcriptional changes.

Correlative light and electron microscopy identifies circuit motifs underlying processing of noisy visual motion in larval zebrafish

The paper uses correlative light and electron microscopy to identify synaptic motifs in larval zebrafish that support visual motion processing.

Subsets of extraocular motoneurons produce kinematically distinct saccades during hunting and exploration.

The paper identifies distinct subsets of extraocular motoneurons in larval zebrafish that produce kinematically different saccades during hunting and exploration.

Mirror-assisted light-sheet microscopy: a simple upgrade to enable bi-directional sample excitation

This paper introduces mirror-assisted light-sheet microscopy to improve imaging of obstructed regions in zebrafish brains.

Standardised Measurements for Monitoring and Comparing Multiphoton Microscope Systems

This protocol provides standardised measurements to assess and compare multiphoton microscope performance across users.

The saccadic repertoire of larval zebrafish reveals kinematically distinct saccades that are used in specific behavioural contexts.

The paper identifies five kinematically distinct saccade types in larval zebrafish and links them to specific behavioural contexts and neural control mechanisms.

A recurrent network architecture explains tectal activity dynamics and experience-dependent behaviour

The paper uses a recurrent network model to explain tectal activity dynamics and their impact on behavior in zebrafish.

Foxd1 dependent induction of temporal retinal character is required for visual function

This study shows that Foxd1 is required for temporal retinal character, which is essential for the development of the high acuity area and visual function in zebrafish.

A structural atlas of the developing zebrafish telencephalon based on spatially-restricted transgene expression

The paper maps the development of cell populations in the zebrafish telencephalon during eversion using transgene expression and creates a structural atlas.

Loss of slc39a14 causes simultaneous manganese deficiency and hypersensitivity in zebrafish

The paper identifies manganese deficiency and neurotoxicity in zebrafish slc39a14 mutants through transcriptome analysis, revealing key molecular pathways involved in manganese homeostasis disruption.

Central nervous system hypomyelination disrupts axonal conduction and behaviour in larval zebrafish

This study shows that hypomyelination in zebrafish larvae disrupts axonal conduction and behavior, linking myelination to neural circuit function.

Synaptic vesicle fusion along axons is driven by myelination and subsequently accelerates sheath growth in an activity-regulated manner

A calibrated optogenetic toolbox of stable zebrafish opsin lines

The paper develops and calibrates nine zebrafish opsin lines for reliable in vivo optogenetic control of neural activity.

A pretectal command system controls hunting behaviour

This study identifies a pretectal command system in larval zebrafish that drives hunting behavior through optogenetic stimulation and ablation experiments.

Compensatory mechanisms render Tcf7l1a dispensable for eye formation despite its requirement in eye field specification

The paper shows that Tcf7l1a is essential for eye field specification in zebrafish but not for eye development, as mutants develop normal eyes through compensatory mechanisms.

Gaze-stabilizing central vestibular neurons project asymmetrically to extraocular motoneuron pools

The paper identifies asymmetric projections of central vestibular neurons in zebrafish and shows how these projections enhance sensory encoding of nose-up stimuli while maintaining gaze stabilization.

Whole-Brain Serial-Section Electron Microscopy In Larval Zebrafish

The paper presents whole-brain serial-section electron microscopy data of a larval zebrafish, enabling reconstruction of neuronal processes and analysis of axonal symmetry and connectivity.