Author

Jiewei Jiang

University of California San DiegoORCID 0000-0001-5497-9371Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Fleur M. FergusoniD· 3 shared Gillian E. GadboisiD· 2 shared Alexander Joel FederationiD· 1 shared Alyssa L. VeranoiD· 1 shared Andrea Gutierrez· 1 shared Andrew J. TaoiD· 1 shared Andrew M. LowyiD· 1 shared Angela T. Fan· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCancer Biology

Fleur M. FergusonORCID

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3 papers

Recent·Most cited

Cancer BiologyRSC Chemical BiologyPeer-reviewedJan 1, 2026

Development of PROTACs for targeted degradation of oncogenic TRK fusions

Saurav Kumar, Jiewei Jiang, Mia S. Donald-Paladino…·Behnam Nabet

This paper develops PROTACs to degrade oncogenic TRK fusions, showing improved efficacy compared to traditional inhibitors.

3 citationstop 4%

humanexperimental assay

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Cancer BiologyNature Chemical BiologyPeer-reviewedAug 11, 2025

ZBTB11 Depletion Targets Metabolic Vulnerabilities in K-Ras Inhibitor Resistant PDAC

Nathan L. Tran, Jiewei Jiang, Mengyao Ma…·Fleur M. Ferguson

This study develops ZBTB11 degraders to target metabolic vulnerabilities in K-Ras inhibitor-resistant PDAC, showing improved anti-cancer activity with reduced toxicity to neurons.

12 citationstop 4%

humanproteomics

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Pharmacology & ToxicologyAngewandte Chemie International EditionPeer-reviewedNov 27, 2024

A Kinetic Scout Approach Accelerates Targeted Protein Degrader Development

Angela T. Fan, Gillian E. Gadbois, Hai‐Tsang Huang…·Fleur M. Ferguson

This study develops a kinetic scout approach to accelerate targeted protein degrader development by tuning ligand residence time through chemical proteomics and mechanistic assays.

10 citations

proteomicsexperimental assay

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