Author

Cheryl E. G. Leyns

Merck & Co., Inc., Rahway, NJ, USA (United States)ORCID 0000-0001-5513-7758Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Matthew J. Fell· 2 shared Michael X. HendersoniD· 2 shared Virginia M.‐Y. LeeiD· 2 shared Alice PrigentiD· 1 shared Bin ZhangiD· 1 shared Brenna BeezholdiD· 1 shared Connor M. WebbiD· 1 shared Daniella DeWeerdiD· 1 shared

Activity by Year

2023-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersNeuroscience

Matthew J. Fell

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2 papers

Recent·Most cited

NeuroscienceTranslational NeurodegenerationPeer-reviewedMar 4, 2024

LRRK2 kinase inhibition reverses G2019S mutation-dependent effects on tau pathology spread

Noah Lubben, Julia K. Brynildsen, Connor M. Webb…·Michael X. Henderson

This study shows that LRRK2 kinase inhibition reverses tau pathology progression in mice with the G2019S mutation but not in wildtype mice.

22 citationstop 3%

mouseexperimental assay

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Neurosciencenpj Parkinson s DiseasePeer-reviewedMay 11, 2023

Glucocerebrosidase activity and lipid levels are related to protein pathologies in Parkinson's disease

Cheryl E. G. Leyns, Alice Prigent, Brenna Beezhold…·Michael X. Henderson

The paper examines the relationship between glucocerebrosidase activity, lipid levels, and protein pathologies in Parkinson's disease and dementia with Lewy bodies.

39 citationstop 2%

humanproteomics

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