Justin R. Meyer

The paper tests the evolutionary safety of CRISPR-Cas9 gene drives in yeast by measuring their impact on mutation rates and loss-of-heterozygosity, finding minimal effects.

The paper demonstrates that experimental phage evolution can expand the host range of phages to kill multidrug-resistant and extensively-drug-resistant Klebsiella pneumoniae isolates.

The paper studies a phage lacking PhuZ, showing it replicates efficiently without this protein, highlighting variation in nucleus-based replication pathways.

This paper develops methods to detect and optimize sampling for multiphasic virus decay, applying them to show that 94% of phage ΦD9 decays 16-fold faster than the remaining population.

The paper shows that cryptic host phenotypic heterogeneity drives diversification of bacteriophage λ through receptor expression oscillations and negative frequency-dependent selection.

This study shows that bacteriophage Φ21 evolves new host receptor usage through destabilizing mutations that create non-genetic phenotypic heterogeneity in viral particles.

The paper uses machine learning to predict phage-bacteria interactions from genome sequences and phenotypic data, achieving 86% accuracy in predicting interactions and reducing error by 40%.