Author

François Massart

University of LuxembourgORCID 0000-0001-5590-3344Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 3 Cell Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:differential expression· 2 Assay:ATAC-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Rejko KrügeriD· 5 shared Paul M. A. AntonyiD· 3 shared Bruno F. R. SantosiD· 2 shared Gérald Cruciani· 2 shared Jochen OhnmachtiD· 2 shared Lasse SinkkoneniD· 2 shared Peter A. BarbutiiD· 2 shared Rashi HalderiD· 2 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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5 shared papersNeuroscience

Rejko KrügerORCID

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5 papers

Recent·Most cited

Cell BiologybioRxivPreprintOct 23, 2026

Generation of an induced pluripotent stem cell line, LCSBi021-A, from a Parkinson's disease patient harboring the missense mutation c.213C>G (p.Ser71Arg) in the RAB32 gene

Ioanna Boumpoureka, Vyron A. Gorgogietas, Elizabet Petkovski…·Rejko Krüger

The paper generates iPSCs from a Parkinson's patient with a RAB32 mutation and confirms their pluripotency and differentiation potential.

DOI 10.64898/2026.10.20.760406

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintOct 31, 2024

DJ-1 mediates regulation of metabolism and immune response in Parkinsons disease astrocytes and Glioblastoma cells

Pauline Mencke, Jochen Ohnmacht, Félicia Jeannelle…·Ibrahim Boussaad

This study shows DJ-1 affects metabolism and immune response differently in Parkinson's disease and glioblastoma cells, with antioxidant treatment rescuing PD-related phenotypes.

DOI 10.1101/2024.10.31.621212

humanbulk RNA-seq

𝕏 PostBluesky

GenomicsbioRxivPreprintJan 27, 2023

Multi-omics analysis identifies LBX1 and NHLH1 as central regulators of human midbrain dopaminergic neuron differentiation

Borja Gomez Ramos, Jochen Ohnmacht, Nikola de Lange…·Lasse Sinkkonen

1 citation

humanbulk RNA-seq

𝕏 PostBluesky

NeurosciencebioRxivPreprintNov 5, 2020

Gene-corrected Parkinson's disease neurons show the A30P alpha-synuclein point mutation leads to reduced neuronal branching and function

Peter A. Barbuti, Bruno F. R. Santos, Paul M. A. Antony…·Rejko Krüger

This study shows that the A30P alpha-synuclein mutation in Parkinson's disease neurons reduces branching and function, with mitochondrial dysfunction and susceptibility to Rotenone.

3 citations

𝕏 PostBluesky

NeurosciencebioRxivPreprintApr 27, 2020

IPSC-derived midbrain astrocytes from Parkinson's disease patients carrying pathogenic SNCA mutations exhibit alpha-synuclein aggregation, mitochondrial fragmentation and excess calcium release

Peter A. Barbuti, Paul M. A. Antony, Gabriella Novak…·Rejko Krüger

6 citations

humanexperimental assay

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