Caroline Hoppe

The paper investigates how Lamin A/C influences chromatin structure during early mammalian lineage segregation, showing its role in maintaining trophectoderm identity.

The paper investigates the developmental fate of zebrafish embryos lacking the reprogramming factors Nanog, Pou5f3, and Sox19b, finding that cells can acquire novel cell states or primordial germ cell-like states.

This paper introduces GEARs, a toolkit for visualizing and manipulating endogenous proteins in vivo, demonstrating its use with Nanog and Vangl2 in zebrafish.

The paper introduces a scalable method to infer transcriptional kinetic parameters from MS2-McP time series data, enabling efficient analysis of promoter activity in Drosophila embryos.

The paper uses the SunTag system to study zygotic hb mRNA translation dynamics in Drosophila embryos, showing translational repression and spatial restriction over time.

The paper shows that BMP signaling modulates transcriptional burst frequency by altering promoter activation rate in Drosophila embryos, leading to graded mRNA output across expression domains.