Author

Tim A.O. Muntslag

Southampton General HospitalORCID 0000-0001-5624-0300Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

David A. MenassaiD· 2 shared Diego Gómez‐NicolaiD· 2 shared María Martín‐EstebanéiD· 2 shared Adrián Olmos‐Alonso· 1 shared Bethany Turnbull· 1 shared Daniel Thomas· 1 shared Gemma L. Fryatt· 1 shared István AdorjániD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersNeuroscience

David A. MenassaORCID

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2 papers

Recent·Most cited

NeuroscienceDevelopmental CellPeer-reviewedAug 16, 2022

Spatiotemporal dynamics of human microglia are linked with brain developmental processes across the lifespan

David A. Menassa, Tim A.O. Muntslag, María Martín‐Estebané…·Diego Gómez‐Nicola

This study examines microglial dynamics across the human lifespan using postmortem tissues and RNAseq data, revealing novel developmental patterns linked to neurodevelopmental milestones.

105 citationstop 2%

humanbulk RNA-seq

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NeuroscienceCell ReportsPeer-reviewedJun 1, 2021

Replicative senescence dictates the emergence of disease-associated microglia and contributes to Abeta pathology

Yanling Hu, Gemma L. Fryatt, Mohammadmersad Ghorbani…·Diego Gómez‐Nicola

This study shows that excessive microglial proliferation in Alzheimer's disease leads to replicative senescence and disease-associated microglia, contributing to Aβ pathology.

298 citationstop 1%

humanbulk RNA-seq

𝕏 PostBluesky