Author

Daniel Thomas

Southampton General HospitalPrimary ORCID profile (0000-0002-0639-3138 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Daniel ThomasiD1 paper

Biology Disciplines

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Neuroscience· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Adrián Olmos‐Alonso· 1 shared Alex K. ShalekiD· 1 shared Allon WagneriD· 1 shared Andreas FeißtiD· 1 shared Anna C. AschenbrenneriD· 1 shared Arik HorneiD· 1 shared Benedikt ReiziD· 1 shared Carmen PizarroiD· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperNeuroscience

Adrián Olmos‐Alonso

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2 papers

Recent·Most cited

Replicative senescence dictates the emergence of disease-associated microglia and contributes to Abeta pathology

Yanling Hu, Gemma L. Fryatt, Mohammadmersad Ghorbani, Juliane Obst, David A. Menassa, María Martín‐Estebané, Tim A.O. Muntslag, Adrián Olmos‐Alonso, Monica Guerrero‐Carrasco, Daniel Thomas, Mark Steven Cragg, Diego Gómez‐Nicola

This study shows that excessive microglial proliferation in Alzheimer's disease leads to replicative senescence and disease-associated microglia, contributing to Aβ pathology.

Cell Reports · Jun 1, 2021Peer-reviewedNeuroscience

Alterations of multiple alveolar macrophage states in chronic obstructive pulmonary disease

Kevin E. Bassler, Wataru Fujii, Theodore S. Kapellos, Arik Horne, Benedikt Reiz, Erika Dudkin, Malte D. Luecken, Nico Reusch, Collins Osei-Sarpong, Stefanie Warnat‐Herresthal, Allon Wagner, Lorenzo Bonaguro, Patrick Günther, Carmen Pizarro, Tina Schreiber, , Joachim Ludwig Schultze

This study uses single-cell RNA-seq and computational methods to analyze macrophage states in COPD patients, revealing transcriptional changes and metabolic shifts associated with the disease.

bioRxiv · May 28, 2020 · PreprintSystems Biology