Dimitris Katsanos

The paper introduces NanoDam, a method for tissue-specific transcription factor profiling in C. elegans using endogenous GFP-tagged TFs and nanobody-Dam fusions, identifying novel targets in specific cell types.

The paper introduces Targeted DamID (TaDa) to identify tissue-specific transcription factor targets in C. elegans and validates its use in studying LIN-22 and NHR-25 in epidermal cell differentiation.

The paper shows that a single amino acid deletion in the heat shock protein HSP-110 in the C. elegans isolate CB4856 reduces the expressivity of a mutation in egl-18.

The paper shows that increased temperature causes a cell fate switch in C. elegans seam cells through changes in the Wnt asymmetry pathway, leading to symmetric cell divisions and increased seam cell numbers.