Yutong Xiao

The paper introduces NanoDam, a method for tissue-specific transcription factor profiling in C. elegans using endogenous GFP-tagged TFs and nanobody-Dam fusions, identifying novel targets in specific cell types.

The paper identifies mutations in E3 ubiquitin ligases that restore development in SWI/SNF mutants in C. elegans, suggesting potential therapeutic targets for human developmental disorders.

This paper introduces a FLP-ON::TIR1 system for precise spatiotemporal protein degradation in C. elegans, showing it can drive efficient target protein degradation in specific cell types.

The paper shows that BAF and PBAF SWI/SNF complexes differentially regulate cell cycle arrest and invasion in C. elegans anchor cells.