Abbey L. Perl

Regulation of the desmosome-intermediate filament linkage enables an adaptive mechano-response within the stratified epidermis

This study identifies the desmosome-intermediate filament network as critical for mechano-response in epidermis, showing its regulation by PP2A-mediated phosphorylation of desmoplakin.

Transcriptional profiling of rare acantholytic disorders suggests common mechanisms of pathogenesis

This paper performs RNA-seq on skin samples from three acantholytic diseases to identify shared transcriptomic features and mechanisms of pathogenesis.