Author

Roddy S. O’Connor

Parker Institute for Cancer ImmunotherapyORCID 0000-0001-5645-4544Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:CITE-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Golnaz VahediiD· 2 shared Adam G. ChatoffiD· 1 shared Aditi ChandraiD· 1 shared Alexander J. DimitriiD· 1 shared Alexander T. DilsiD· 1 shared Alison JaccardiD· 1 shared Amy E. BaxteriD· 1 shared Andrea Andress HuacachinoiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

Golnaz VahediORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintOct 6, 2026

Nutrient-sensitive histone propionylation regulates T cell fate and function

Alison Jaccard, Kelly Rome, Qihua Yang…·Kathryn E. Wellen

This study shows that histone propionylation, influenced by nutrient availability, regulates T cell fate and antitumor immunity.

DOI 10.64898/2026.10.01.756002

humanproteomics

𝕏 PostBluesky

ImmunologyScience AdvancesPeer-reviewedNov 13, 2024

TET2 regulates early and late transitions in exhausted CD8+ T-cell differentiation and limits CAR T-cell function

Alexander J. Dimitri, Amy E. Baxter, Gregory M. Chen…·Joseph A. Fraietta

This study shows that targeting TET2 in CAR T-cells improves their anti-tumor responses by limiting terminal exhaustion and enhancing therapeutic potential.

42 citationstop 2%

𝕏 PostBluesky