Simulated spaceflight disrupts the immune-gut-brain axis and drives sex-dependent neuroinflammation, axonal injury, and behavioral deficits.
Marissa Burke, Göknur Kara, Morgan Holcomb…·Sonia Villapol
This study shows that simulated spaceflight stressors disrupt the immune-gut-brain axis, causing sex-dependent neuroinflammation, axonal injury, and behavioral issues in mice.