Biana Godin

Codon optimality modulates cellular stress and innate immune responses triggered by exogenous RNAs

This study shows that codon optimality affects RNA translatability, stress responses, and immune activation, highlighting its importance for RNA-based therapeutics.

Telomerase mRNA-Lipid nanoparticles attenuate neuroinflammation after traumatic brain injury in mice

This paper shows that delivering telomerase mRNA via lipid nanoparticles reduces neuroinflammation and oxidative stress after traumatic brain injury in mice.

Telomerase mRNA Reduces Radiation-induced DNA Damage of human skin

This study shows that telomerase mRNA reduces radiation-induced DNA damage in human skin cells by enhancing DNA repair and reducing mitochondrial ROS without extending telomere length.

Sex-dependent improvement in traumatic brain injury outcomes after liposomal delivery of dexamethasone in mice.

This study shows that liposomal dexamethasone reduces TBI lesion volume and inflammation in male mice but not females.